mixed solid and cystic thyroid nodule

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Most thyroid nodules dont cause symptoms. If you have thyroid nodules, you should also be checked for hyperthyroidism or hypothyroidism. An official website of the United States government. Curious about high TSH levels and fertility? During this test, an isotope of radioactive iodine is injected into a vein in your arm. See below for individual systems. Giles WH, Maclellan RA, Gawande AA, Ruan DT, Alexander EK, Moore FD Jr, Cho NL. /TrimBox [ 9 9 594 792 ] Elsevier; 2020. https://www.clinicalkey.com. They can sometimes be confused with swollen lymph nodes, which are part of the bodys immune system. Solid nodules in your thyroid are more likely to be malignant than fluid-filled nodules, but theyre still rarely cancerous. >> In: Rosai and Ackerman's Surgical Pathology. Saccharomyces boulardii and infection due to Giardia lamblia. Ross DS. Even though most thyroid nodules arent cancer, they can sometimes be a sign of and/or cause thyroid disease. our/R/b/w/F/period/five/three/U/v/comma/V/six/seven) FOIA Although there is limited research, acupuncture may help manage hyperthyroidism symptoms. endobj Bookshelf Even though the majority of thyroid nodules are benign and cause no other symptoms, its still important to have the nodule evaluated in the small chance that its cancer. /Subtype /Type1 Results: A total of 704 nodules had echogenic foci; 246 did not. Ultrasonography. But even larger thyroid nodules are treatable, sometimes even without surgery. I have a right thyroid nodule that is well-circumscribed isoechoic solid nodule with a thin hypoechoic halo and small cystic space 1.71x1.53x1.19cm volume:1.6cc previous was 1.05x1.05x0.78cm vol:0.45cc after 3 yrs. /Type /FontDescriptor Comparison of diagnostic accuracy and utility of artificial intelligence-optimized ACR TI-RADS and original ACR TI-RADS: a multi-center validation study based on 2061 thyroid nodules. 0000018008 00000 n It may also include an ultrasound. Thyroid nodules are very common, especially in the U.S. Accessibility The Future of Functional Medicine Review: The majority of thyroid nodules are benign and not a cause for concern. 0000031624 00000 n Probiotics are an effective way to balance your gut microbiome with few side effects. /Resources 42 0 R When nodules with microcalcifications are seen, the doctor may advise to have Thyroid nodules on ct. us found 10+ nodules, 2 largest about 2.5 cm and are "mixed cystic and solid". WebMixed cystic and solid thyroid nodule A 56-year-old female asked: Thyroid nodules on ct. us found 10+ nodules, 2 largest about 2.5 cm and are "mixed cystic and solid". {"url":"/signup-modal-props.json?lang=us"}, Morgan M, Jones J, Knipe H, et al. 0000027875 00000 n If small nodules are less than 1 cm or filled with fluid, they are almost always benign. 0000036724 00000 n what does this mean? doi: 10.1001/jamainternmed.2013.9245. Patients usually return home or to work after the biopsy without any ill effects. /XHeight 502 (2005). << Thyroid fine needle aspiration biopsy (FNAB): Change In Thyroid Nodule Volume Calculator, Find an Endocrinology Thyroid Specialist, http://www.thyroid.org/cancer-of-the-thyroid-gland, http://www.thyroid.org/what-are-thyroid-nodules, Clinical Thyroidology for the Public (CTFP). >> is this high chance of malignant? HTQmL[euR@+:6AT&&D5M} dCpe,A2gdXvn95ysN<4G4-2]r 'hA/]88d*O-w6l {ly4ZZKrfsy^g'Z67o=.dp5N+_ms8=-OWfHkt6fq ESZOQ(*3(-MT" OQ#,7q"ML Ra-YYd@ue$31E*C6lO28'f{l$6]rB5ivYLPiE:uOfJnqE?Tm|A5}[UKSrDA5f x;E%>!#a l' 2008;27(2):215-23. Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. 500 500 500 444 795 611 611 556 611 500 444 611 611 278 500 556 444 833 667 There were more malignancies in group 2 than the other groups (p = 0.040). Gaberek S, Gaberek B, Zaletel K. Incidence of thyroid disorders in the second decade of adequate iodine supply in Slovenia [published online ahead of print, 2020 May 6]. Decrease in TSH levels after lactose restriction in Hashimotos thyroiditis patients with lactose intolerance. 0000011397 00000 n Thyroid. Aydoan B, Ceyhan K, ahin M, orapolu D. Are Thyroid Nodules with Spongiform Morphology Always Benign? Increased levels of insulin-like growth factor-1 (a. Overview of thyroid nodule formation. government site. 0000036123 00000 n Some are solid, and some are fluid-filled cysts. Written by Dr. Michael Ruscio, DC on Virili C, Bassotti G, Santaguida MG, et al. Reference article, Radiopaedia.org (Accessed on 04 Mar 2023) https://doi.org/10.53347/rID-35024. Most thyroid nodules are benign, which means they arent cancerous. Accessed Nov. 4, 2019. A thyroid nodule is an unusual lump (growth) of cells on your thyroid gland. Your doctor then sends the samples to a laboratory to have them analyzed under a microscope. /F7 62 0 R /F8 65 0 R /F9 68 0 R /F10 71 0 R /F11 74 0 R /F12 77 0 R /F13 Treatment depends on the type of thyroid nodule you have. Healthcare providers detect them in approximately 5% to 7% of adults during a physical examination. However, theyre about four times more common in people assigned female at birth than people assigned male at birth. If your thyroid nodule is benign, you can address it via the gut-thyroid axis (the foundational relationship between your thyroid and gut). << 0000037219 00000 n All rights reserved. Thyroid nodules are common and occur in up to 50% of the adult population; however, less than 7% of thyroid nodules are malignant. << Heres when you should pay attention to a thyroid nodule: In a majority of cases, thyroid nodules are caused by Hashimotos thyroiditis, an autoimmune attack on the thyroid gland that causes scarring. Mayo Clinic is a not-for-profit organization. Dr. Michael Ruscio, DC. 6. Mixed solid and cystic nodules are the most common finding in thyroid US and are often hyperplastic benign nodules with degeneration and internal debris as Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. 2022 Nov;5(6):e373. Even a benign growth on your thyroid gland can cause symptoms. 0000046197 00000 n /Filter /FlateDecode Join endocrinologist Paul Ladenson, M.D., as he outlines the signs and symptoms of the various thyroid disorders and discusses the interplay among other diseases and the thyroid. However, if you have several nodules or large nodules, you may be able to see them. We are vaccinating all eligible patients. 2016 Nov;26(11):1645. doi: 10.1089/thy.2016.0389. You're also likely to have another biopsy if the nodule grows larger. AJR Am J Roentgenol. Echogenic Foci in Thyroid Nodules: Significance of Posterior Acoustic Artifacts. endstream Depending on the type of thyroid nodule, it can be solid or filled with fluid, in which case its called a thyroid cyst. /StemV 200 However, today more limited surgery to remove only half of the thyroid may be appropriate for some cancerous nodules. endobj 0000018261 00000 n Liu Y, Li X, Yan C, Liu L, Liao Y, Zeng H, Huang W, Li Q, Tao N, Zhou J. Eur Radiol. The https:// ensures that you are connecting to the WebThe thyroid gland is located in the lower front of the neck, below the voicebox (larynx) and above the collarbones. Fine needle aspiration biopsy (FNAB) is the best way to find out whether a thyroid nodule is cancerous or benign. In some cases, nodules that take up less of the isotope called cold nodules are cancerous. [7, 8, 9]. /N 4 Find more COVID-19 testing locations on Maryland.gov. This logic falls apart in light of research that connects excessive iodine with an increase in thyroid autoimmunity, goiter, and hypothyroidism. 2022 Jun;279(6):3139-3146. doi: 10.1007/s00405-021-07151-3. A newer alternative that the doctor can use to treat benign nodules in an office setting is called radiofrequency ablation (RFA). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. The prognosis for noncancerous (benign) thyroid nodules is great. Thyroid nodule. 2012 Sep-Oct;13(5):530-5. doi: 10.3348/kjr.2012.13.5.530. The doctor uses a very thin needle to withdraw cells from the thyroid nodule. 0000009119 00000 n Here are two research-backed steps you can take to improve your thyroid health. /Size 95 2007;27(3):847-60. Li W, Zhu Q, Jiang Y, Zhang Q, Meng Z, Sun J, Li J, Dai Q. Hoang JK, et al. 94 0 obj Unauthorized use of these marks is strictly prohibited. Methods: /Pages 35 0 R Tests include: Physical exam. The role of Helicobacter pylori in patients with hypothyroidism in whom could not be achieved normal thyrotropin levels despite treatment with high doses of thyroxine [published correction appears in Helicobacter. Solid hypoechoic 1.4 x 0.6 x 0.4 cm nodule in the right thyroid isthmus TR 4. Studies report on possibility of thyroid cancer in about 5% of thyroid nodules. Fu Y, Sun Y, Pei Q, Han X, Qin W, Mei F, Tan S, Cui L. Medicina (Kaunas). 42 0 obj Ann Surg Oncol. Foley TP Jr. Epub 2021 Aug 23. Thyroid nodules are very common. Your provider may also discover a nodule with an imaging test done for another reason. Follow-up of atypia and follicular lesions of undetermined significance in thyroid fine needle aspiration cytology. Choosing an experienced specialist can mean more options to help personalize your treatment and achieve better results. /Parent 35 0 R A total of 96 patients diagnosed with cancer were matched for age, sex and year of ultrasonography with 369 controls with benign thyroid nodules. WebComprehensive summary of TIRADS for reporting thyroid nodules on ultrasound for Radiologists and Sonographers ! >> Thyroid nodules that is complex and solid nodule. Our team of licensed nutritionists and dietitians strive to be objective, unbiased, honest and to present both sides of the argument. National Library of Medicine In the past, it was standard to remove a majority of thyroid tissue a procedure called near-total thyroidectomy. Cytopathology. 2018; doi:10.1097/CAD.0000000000000617. WebLarge, cystic/solid, and thyroid nodules with both characteristics had false-negative rates of 17%, 25%, and 30%, respectively, compared with 0%, 9%, and 17% for small (less than 3 At Another Johns Hopkins Member Hospital: The Johns Hopkins Thyroid and Parathyroid Center, Webinar: Thyroid Disease, an Often Surprising Diagnosis, Masks are required inside all of our care facilities, COVID-19 testing locations on Maryland.gov, Radiofrequency Ablation for Thyroid Nodules. Surgery. WebLikely benign: Thyroid lesions are classified as solid or cystic or a combination of both. Complex nodules are common. If one of the nodules starts getting appreciably bigger while the rest stay the same, get seen. Whether its benign or not, a bothersome thyroid nodule can often be successfully managed. /Length 232 You can usually breastfeed if you have hyperthyroidism. My husband has been diagnosed with thyroid nodules which are solid and have micro calcifications. 0000045880 00000 n The object of this study was to evaluate the frequency of malignancy in mixed echoic thyroid nodules and ascertain the ultrasound findings that help distinguish benign from malignant nodules. Thyroid cancer management: From a suspicious nodule to targeted therapy. WebAbstract. If you want to put a plan together to support your thyroid health, consider taking my thyroid course or reach out to us at the Ruscio Institute. Cellini M, Santaguida MG, Virili C, et al. 1. 2015 Jan;22(1):152-7. doi: 10.1245/s10434-014-3952-7. The incidental thyroid nodule. However, its still important to see your healthcare provider if you notice a lump on your thyroid (in the front of your neck). HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. DOI: cancer.org/cancer/thyroid-cancer/about/what-is-thyroid-cancer.html, sciencedirect.com/topics/medicine-and-dentistry/echogenicity, mayoclinic.org/diseases-conditions/thyroid-nodules/symptoms-causes/syc-20355262, thyroid.org/wp-content/uploads/publications/ctfp/volume7/issue1/ct_public_v71_6_7.pdf, nibib.nih.gov/science-education/science-topics/ultrasound, What You Should Know About Thyroid Nodules, Most Benign Thyroid Nodules Remain Noncancerous, Even If They Grow. Thyroid nodules are very common and a large portion are mixed echoic, with both solid and cystic areas. /Encoding /WinAnsiEncoding /Widths [ 222 333 222 278 444 444 444 444 444 444 444 444 444 444 222 222 RESULTS. Accessed Oct. 31, 2019. Thyroid nodules that had the highest probability of malignancy were those that were large (3 cm or larger), cystic/solid, or large and cystic/solid. @ qTzlyA{jT=$uRAp?B!I$kL1?~U9_Kj3' 4&`m3j2lqcSp~*j1wa: SRBAZ5C D6zQ S In other cases, the nodules can get big enough to cause problems. Thyroid nodules are very common, and theyre usually not a cause for concern. Careers. PKakpG! While swollen lymph nodes can potentially point to thyroid issues, they are not a part of the endocrine (hormone) system and are more likely signaling something else. New guidelines for the management of thyroid nodules and differentiated thyroid cancer. Partially cystic thyroid nodules in ultrasound-guided fine needle aspiration: Prevalence of thyroid carcinoma and ultrasound features. A thyroid nodule is a lump in or on the thyroid gland. In fact, experts estimate that about half of Americans will have one by the time theyre 60 years old. THE FULL ARTICLE TITLE: /Contents [ 85 0 R 86 0 R 87 0 R 88 0 R 89 0 R 90 0 R 91 0 R 92 0 R ] False negative cytology in large thyroid nodules. 2018; doi:10.3322/caac.21447. A thyroid nodule is an unusual lump (growth) of cells on your thyroid gland. But your doctor will also want to know if your thyroid is functioning properly. Surgery to remove the gland typically addresses the problem, and recurrences or spread of the cancer cells are both uncommon. They also occur more often in people who live in countries in which food isnt fortified with iodine. 0000041546 00000 n sharing sensitive information, make sure youre on a federal 0000008824 00000 n 2022 Oct 20;12:1013410. doi: 10.3389/fonc.2022.1013410. Korean J Radiol. Kim D, Eun C, In H, Kim M, Jung S, Bae S. Sonographic Differentiation of Asymptomatic Diffuse Thyroid Disease from Normal Thyroid: A Prospective Study. doi: 10.1097/MD.0000000000008689. The vast majority more than 95% of thyroid nodules are benign (noncancerous). E5X`>E#}Q)MgJ5/?f[O>LYz$/ 9ovKdrr"xl)%. HlUyPgdHGF1hQT$!8;\b DVo`hV\A$XqjkZL|{^ZE4=:6.::DHoQ:{25?z2Sr3MH 41}"y1%*kw&G);Hn3Rl5)L3v'aRm.d_9R\{no5|YHQcUT Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. 0000019616 00000 n A diagnosis of cancer was made in 10.5% of nodules measuring 1 1.9 cm. >> The aim of this study was to assess (3) Amazon and the Amazon logo are trademarks of Amazon.com, Inc, or its affiliates. Elselvier; 2018. https://www.clinicalkey.com. Our thyroid experts in the head and neck endocrine surgery team diagnose and treat patients with a variety of thyroid and parathyroid conditions. 48 0 obj Understanding the risks and harms of management of incidental thyroid nodules: A review. /Ascent 722 2014;52(6):1283-94. Get useful, helpful and relevant health + wellness information. In most cases, thyroid nodules arent a cause for concern. Some health care providers recommend iodine supplementation to support thyroid health, sometimes in very high doses. 0000020734 00000 n << A thyroid nodule may be worth a closer look if its larger than 1 cm or painful, or if youre also experiencing symptoms related to hypo- or hyperthyroidism. Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Cystic (fluid-filled). /S 152 4 Some investigators have Other factors that lead to an increased risk of thyroid nodules include: Thyroid nodules are common. Risk Stratification of Thyroid Nodules: From Ultrasound Features to TIRADS. If a thyroid nodule is producing thyroid hormones, overloading your thyroid gland's normal hormone production levels, your doctor may recommend treating you for hyperthyroidism. In rare cases, they're cancerous. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). If your entire thyroid is swollen enough to be visible, then its a goiter and may also require treatment. /FontFile3 45 0 R startxref The changing incidence of thyroid cancer. 8600 Rockville Pike The procedure is usually done in your doctor's office, takes about 20 minutes and has few risks. No, say experts at Johns Hopkins Department of Otolaryngology and Head and Neck Surgery. 2017 Nov;96(46):e8689. A positive thyroglobulin test doesnt quite rule out Hashimotos or Graves disease. trailer Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimotos Thyroiditis. Your doctor will likely ask you to swallow while he or she examines your thyroid because a nodule in your thyroid gland will usually move up and down during swallowing. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. This article is based on scientific evidence, written by experts and fact checked by experts. Muscle weakness is a common symptom of hyperthyroidism caused by hormonal imbalances. 44 0 obj << Both prospective and retrospective studies were included. /ExtGState << /GS2 84 0 R >> HHS Vulnerability Disclosure, Help 0000001713 00000 n 0000004788 00000 n Multiple (more than one nodule). Find out what is holistic dentistry and its approach to mercury fillings, fluoride, and improving oral health. 0000048374 00000 n /FirstChar 44 Krysiak R, Szkrbka W, Okopie B. Clipboard, Search History, and several other advanced features are temporarily unavailable. However, it is possible to have nodules in addition to a goiter, making it a multinodular goiter. Thyroid scan. This thyroid tissue damage can lead to underproduction of thyroid hormones, leading to hypothyroid symptoms such as: In some cases, benign thyroid nodules produce additional thyroxine, a hormone secreted by your thyroid gland. >> As has been noted for completely solid nodules, microcalcifications are associated with an increased risk of malignancy. The nodules were divided into the following three groups. Masks are required inside all of our care facilities. WebOBJECTIVE: Our research sought to investigate the relationship between initial ablation ratio (IAR) and internal composition of benign thyroid nodules treated by microwave ablation (MWA). xc```c``i Bl,;wO2[A$DM'E._4kPI}i.n_8m^GR_j5 =z,&lkxhr?s(R|wBA;ami+>=PV|X'4kK\K RE[ 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (http://www.thyroid.org/wp-content/uploads/patients/brochures/Nodules_brochure.pdf). followup needed? Yang J, Sun Y, Li X, Zhao Y, Han X, Chen G, Ding W, Li R, Wang J, Xiao F, Liu C, Xu S. Front Oncol. Some patients are good candidates for a scarless thyroid procedure, where the surgeon reaches the thyroid through an incision made on the inside of your lower lip. Its simply a sign that your doctor may need to do additional testing, such as a biopsy. Treatment options include: Since researchers dont know what causes the majority of thyroid nodules, you cant prevent them in most cases. 0000051727 00000 n Leave a comment or connect with me on social media asking any health question you may have and I just might incorporate it into our next listener questions podcast episode just for you! WebINTRODUCTION. About 2 or 3 in 20 are malignant, or cancerous. Careers. However, if a thyroid cyst continues to expand it may require treatment. 5nj!R WE?r @yhO biVwK|q} 7oZ#q`q"'gWeKUW`'0w?[h z!+m;lH$I I Data analysis of this study showed that only 3 ultrasound features were related with the risk of cancer: microcalcification, nodule size greater than 2 cm, and solid form. /Descent -190 /CapHeight 722 Although calcification can be seen in both benign and malignant processes, it is the ultrasound feature most closely associated with malignancy 1. /MediaBox [ 9 9 594 792 ] MeSH 0000018873 00000 n Although widespread use of ultrasonography (US) has exponentially increased thyroid nodule detection to about 19.067.0%, malignancy is found in only about 9.015.0% of nodules evaluated using fine-needle aspiration (FNA) [1,2,3].To minimize potential harm from overuse of FNA, the Thyroid Imaging Reporting and Data System (TIRADS) was 0000018679 00000 n 2017; doi:10.1001/jamaoto.2017.0003. 0000050067 00000 n National Institute of Diabetes and Digestive and Kidney Diseases. Even though thyroid nodules are almost always noncancerous (benign), the small chance that it could be cancer means that most thyroid nodules need some type of evaluation. 2013 Dec;24(6):385-90. doi: 10.1111/cyt.12021. Accessed Oct. 31, 2019. This site needs JavaScript to work properly. WebNodules were also classified into four parenchymal patterns: hypoechoic, hyperechoic, >50% solid, and cystic. HHS Vulnerability Disclosure, Help 0000008373 00000 n Accessed Oct. 31, 2019. This content does not have an Arabic version. Vojvodich SM, Ballagh RH, Cramer H, Lampe HB. lymph nodes with cystic change are highly suspicious; loss of normal fatty hilum, irregular node appearance; increased color Doppler flow is suspicious; no threshold The American Cancer Society medical and editorial content team. Disclaimer: (1) The information provided on this website is for educational purposes only and is not intended to diagnose or treat any disease. /Info 36 0 R If you see or feel a thyroid nodule yourself usually in the middle of your lower neck, just above your breastbone call your primary care doctor for an appointment to evaluate the lump. The symptoms, diagnosis and treatment of thyroid nodules for children are the same as for adults (as detailed in the above sections). Check for errors and try again. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). All rights reserved. /CharSet (/O/R/I/G/N/A/L/E/S/C/H) 26th ed. During the procedure, your doctor inserts a very thin needle in the nodule and removes a sample of cells. Does a solid 1.1 cm thyroid nodule need to be biopsy? In 2017, the Thyroid Imaging Reporting and Data System (TI-RADS) Committee of the American College of Radiology (ACR) published a white paper that presented a new However, most nodules arent a serious concern. If you notice a bump on your thyroid, its important to see your healthcare provider. /StemH 140 Hashimotos Thyroiditis and Autoimmune Gastritis. Make a donation. Thyroid. An official website of the United States government. Epub 2012 Oct 18. A publication of the American Thyroid Association, Summaries for the Public from Clinical Thyroidology (from recent articles in Clinical Thyroidology) Fine-needle aspiration biopsy. Eur Arch Otorhinolaryngol. Centanni M, Gargano L, Canettieri G, et al. Assuming the cystic nodule turns into a solid nodule, the indication for biopsy will depend on the characteristics of this solid nodule. In: Diagnostic Ultrasound. Last medically reviewed on December 15, 2017, A thyroid nodule is a lump that can develop in your thyroid gland. Bethesda, MD 20894, Web Policies But first, well review what thyroid nodules are. 0000042480 00000 n endobj /Type /Font Epub 2015 Sep 21. In: Ferri's Clinical Advisor 2020. /O 41 What is thyroid cancer? Improving your gut health with an anti-inflammatory diet and probiotics, and optimizing your iodine levels, can often reduce the size of thyroid nodules. Your thyroid gland is a small, butterfly-shaped endocrine gland located in your neck, below your Adam's apple. Learn about what we offer at our center. /Type /Font Some thyroid nodules with true microcalcifications are thyroid cancers. >> Adv Surg. /Prev 343972 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Wong KT, et al. Unable to load your collection due to an error, Unable to load your delegates due to an error. << 0000003108 00000 n endobj 2. Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection. /FontBBox [ -83 -250 1000 969 ] 500 500 500 500 278 500 500 278 278 500 278 722 500 500 500 500 333 444 278 Hormone Health Network. 2017 May;27(5):641-650. doi: 10.1089/thy.2016.0336. official website and that any information you provide is encrypted WebIn fact, the American thyroid association (ATA) Guidelines state that while all solid nodules larger than 1 cm should undergo FNAB, mixed cystic-solid nodules should be biopsied only when size is larger than 1.5 or 2.0 cm in the presence of suspicious US findings, or when size is above 2.0 cm if no suspicious US findings are present. http://www.thyroid.org/hyperthyroidism/. This site complies with the HONcode standard for trustworthy health information: verify here. Impact of Microcalcifications on Risk of Malignancy in Thyroid Nodules with Indeterminate or Benign Cytology.

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